One south-bound lane on the Hume Highway remains closed between Berrima to Sutton Forest following a crash between a car and a truck at Belanglo Road.
This follows both lanes being shut for some time this morning, with traffic banked up as a result.
The incident occurred at about 9.22am and resulted in traffic queues of up to five kilometres.
Motorists are advised to avoid the area due to significant delays.
Transport for NSW and emergency services are in attendance.
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