UPDATE: The south-bound lanes of the Hume Motorway have been reopened. Traffic is still heavy in the area and motorists are advised to allow extra travel time.
PHEASANTS NEST: All southbound lanes have reopened on the Hume Mwy after fatal crash this morning. Allow extra time as delays start to ease.— Live Traffic NSW (@LiveTrafficNSW) March 7, 2017
UPDATE: Two people have died following a crash on the Hume Motorway on Tuesday morning.
Just before 8am on March 7, emergency services responded to a head-on crash in the south-bound lanes of the Hume Highway, about one-kilometre south of Picton Road.
A 49-year-old woman driving a Mazda 4WD died at the scene. A seven-year-old boy and a seven year-old girl, also in the Mazda, were trapped for a short time.
The seven-year-old boy died on arrival at Liverpool Hospital while the seven-year-old girl remains in a critical condition at the Westmead Children’s Hospital.
A 49-year-old woman, driving a Holden Astra, was trapped before she was released and taken by NSW Ambulance paramedics to Liverpool Hospital. She remains in a critical condition.
The next of kin of all parties have been notified.
The Hume Highway south-bound remains closed while crash investigation officers are on scene.
EARLIER: A woman is dead and two children are among a number of people seriously injured in a horrific crash that has closed the Hume Motorway to south-bound traffic near Wilton, south of Sydney.
Emergency services were called to the motorway about 7.50am on Tuesday after two cars were involved in a head-on crash in the motorway's south-bound lanes, about one kilometre south of the Picton Road turn-off.
One of the vehicles rolled onto its roof, and motorists said smoke was coming from the wreckage.
A NSW Police spokeswoman said a woman in one of the vehicles died at the scene.
Emergency service workers are trying to free a second woman who is trapped in the other vehicle. She is believed to be critically injured.
A NSW Ambulance spokesman said paramedics also treated two children involved in the crash.
Those passengers were trapped in a vehicle for a short time, and were being taken to hospital with serious injuries, police said.
Two rescue helicopters have landed on the motorway, and all south-bound lanes have been closed at Picton Road.
Police said the circumstances surrounding the crash were not yet known. Police from the Crash Investigation Unit are on their way to the scene.
The Transport Management Centre warned south-bound motorists to expect significant delays as emergency services attended the crash scene.
The motorway is expected to remain closed to south-bound traffic for some time.